protein-lab

protein-lab

Manages local protein experiments with a Flask backend and SQLite, offering tools for protein library management, Beer-Lambert concentration calculations, BLI dilution planning, and experiment archiving. It provides 7 MCP tools for AI assistants like Claude to interact with the system.

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README

Protein Lab v0.0.1

本地蛋白质实验管理系统。Flask 后端 + 纯 SQLite,无需网络、数据完全本地。

功能

  • 蛋白库 — 手动添加 / FASTA 批量导入 / 搜索匹配
  • 计算工具 — Beer-Lambert 浓度计算(Pace 1995 消光系数,与 Expasy ProtParam 一致)、BLI 梯度稀释规划(递推稀释 + 统一体积 + 整百微升取整)
  • 实验归档 — 从计算工具一键保存 / 按实验导出 Excel / 历史实验回填
  • MCP 服务器 — 7 个工具,供 Claude 等 AI 通过 MCP 协议调用

环境要求

  • Python 3.9+
  • 依赖:pip install -r requirements.txt

启动

双击 启动.bat(Windows)或 启动.command(macOS),浏览器自动打开 http://127.0.0.1:5000。关闭窗口即停止服务。

配置 MCP(可选)

在 Claude Code 的 .claude/settings.json 中添加:

{
  "mcpServers": {
    "protein-lab": {
      "command": "python",
      "args": ["path/to/protein_lab/mcp_server.py"]
    }
  }
}

目录结构

protein_lab/
├── app.py              Flask 主应用
├── calculators.py      计算核心(MW / ε / 浓度 / 稀释)
├── models.py           SQLite 数据模型
├── mcp_server.py       MCP stdio 服务器
├── requirements.txt    依赖
├── 启动.bat            一键启动
├── templates/          Jinja2 页面模板
├── static/             JS + CSS
└── protein_lab.db     自动生成,首次运行创建

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