MGnify MCP Server

MGnify MCP Server

Enables interaction with MGnify metagenomics resources and tools through the Model Context Protocol. Provides access to MGnify's API for querying and analyzing metagenomic datasets and related biological information.

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MGnify MCP Server

This repository implements an MCP server that exposes MGnify resources and tools over the Model Context Protocol.

Prerequisites

  • Python 3.10+ recommended (the mcp SDK requires Python >= 3.10). The project metadata uses a marker to skip installing mcp on older Python, but the server cannot run without it.
  • pip >= 21
  • Optional: Docker

Quick start (Python 3.10+)

  1. Create and activate a virtual environment

    • macOS/Linux: python3 -m venv .venv source .venv/bin/activate
    • Windows (PowerShell): py -3.10 -m venv .venv .venv\Scripts\Activate.ps1
  2. Install the package (editable) and dependencies pip install -e .

  3. Configure environment (optional)

    • Copy .env.example to .env and adjust values as needed cp .env.example .env
    • Available variables:
      • MG_BASE_URL: Override the MGnify API base URL (default: https://www.ebi.ac.uk/metagenomics/api/v1)
      • MG_API_KEY: If you have an API token, it will be sent as Bearer auth
      • BIND, PORT: Only used if you enable the HTTP transport in server.py
  4. Optional: Run a local smoke test (no MCP client needed) python scripts/smoke_test.py

    • This will call the MGnify API via the included client to ensure things work locally.
  5. Run the MCP server (stdio transport) mgnify-mcp

    • The server will run over stdio until the client disconnects. Use an MCP-compatible client/tooling to connect.

Using with Claude Desktop (example)

  • Add to your claude_desktop_config.json or the UI where MCP servers are configured: { "mcpServers": { "mgnify": { "command": "/path/to/venv/bin/mgnify-mcp", "env": { "MG_BASE_URL": "https://www.ebi.ac.uk/metagenomics/api/v1" } } } } Replace the command with the absolute path to your venv script.

Alternative: Docker

  • Build docker build -t mgnify-mcp .
  • Run (stdio is not practical via docker). If you want HTTP transport, uncomment serve_http in mgnify_mcp/server.py and rebuild, then: docker run --rm -p 8173:8173 --env-file .env mgnify-mcp Then configure your client to connect to http://localhost:8173

Troubleshooting

  • pip cannot find mcp / versions ignored require Python >=3.10 Upgrade to Python 3.10 or newer. The server relies on the mcp SDK.
  • SSL or network errors to MGnify API Check MG_BASE_URL and your network. The public API should be reachable without an API key; some endpoints may rate-limit.
  • Rate limiting The server surfaces 429 as an error with retry-after from MGnify. Back off and retry.

Development tips

  • Run unit/lint tools you prefer. The code uses Pydantic v2 for input schemas and Requests for HTTP.
  • Entry point is defined in pyproject.toml: mgnify-mcp -> mgnify_mcp.server:main

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