🧬 BioLab MCP Server

The Stripe for Scientific Data — Unified MCP server providing AI-agent-ready access to AlphaFold, PubMed, ChEMBL, Ensembl, and 37+ scientific databases.

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What is BioLab MCP?

BioLab MCP is a premium Model Context Protocol server that gives AI agents (Claude, Cursor, etc.) direct access to the world's leading scientific databases through a single, reliable interface.

Problem: Researchers and AI developers need data from 10+ incompatible APIs with different auth methods, rate limits, and response formats.

Solution: One MCP server. One API key. All databases. Validated, structured responses.

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🚀 Quick Start

1. Install

git clone https://github.com/your-org/biolab-mcp-server
cd biolab-mcp-server
uv sync

2. Configure Claude Desktop

Add to ~/Library/Application Support/Claude/claude_desktop_config.json (macOS) or %APPDATA%\Claude\claude_desktop_config.json (Windows):

{
  "mcpServers": {
    "biolab": {
      "command": "uv",
      "args": ["run", "--directory", "/path/to/biolab-mcp-server", "biolab-server"]
    }
  }
}

3. Ask Claude

"Search AlphaFold for TP53 protein structure and confidence scores"
"Find the top 10 papers on CRISPR cancer therapy from 2023-2024"
"What drugs target EGFR? Show me IC50 values from ChEMBL"
"Are there any Phase 3 trials recruiting for lung cancer with pembrolizumab?"

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🔬 Available Tools (8 MCP Tools)

Tool	Description	Databases
query_alphafold	Protein structure predictions with pLDDT scores	AlphaFold DB, UniProt
search_pubmed	Scientific literature with metadata extraction	PubMed, PMC
query_chembl	Drug compounds, IC50/Ki bioactivity data	ChEMBL
get_genomic_data	Gene locations and variant frequencies	Ensembl, gnomAD
search_proteins	Protein metadata and interaction networks	UniProt, STRING
get_clinical_trials	Clinical study search and monitoring	ClinicalTrials.gov
find_drug_targets	Disease-gene associations with confidence scores	Open Targets
find_related_papers	Cross-database semantic literature search	PubMed + Semantic Scholar + EuropePMC

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💰 Pricing

Tier	Price	Requests/Month	Databases
Free	$0/month	100	AlphaFold, PubMed, ChEMBL
Researcher	$24/month	5,000	All 37+
Lab	$99/month	50,000	All 37+ + Team keys
Enterprise	Custom	Unlimited	All + Private deploy

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🛠️ Development

Prerequisites

• Python 3.11+
• uv package manager

Setup

# Clone and install
git clone https://github.com/your-org/biolab-mcp-server
cd biolab-mcp-server
uv sync --dev

# Copy environment config
cp .env.example .env

# Generate an API key
uv run biolab generate-key --tier researcher --label "my-key"

Run Tests

uv run pytest tests/ -v

Project Structure

src/biolab/
├── server.py          # MCP Server (stdio transport, 8 tools)
├── auth.py            # API key management (SQLite)
├── cache.py           # Disk-based caching
├── config.py          # Settings via pydantic-settings
├── models.py          # Pydantic response models
├── cli.py             # CLI tools
└── tools/
    ├── alphafold.py   # AlphaFold Database
    ├── pubmed.py      # PubMed / PMC
    ├── chembl.py      # ChEMBL drug database
    ├── genomics.py    # Ensembl + gnomAD
    ├── proteins.py    # UniProt + STRING
    ├── clinical.py    # ClinicalTrials.gov
    ├── targets.py     # Open Targets
    └── literature.py  # Cross-database search

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🏗️ Architecture

Claude / Cursor (MCP Client)
        ↕ JSON-RPC 2.0 (stdio)
BioLab MCP Server (FastAPI + MCP SDK)
        ↕ HTTP + caching
Scientific Databases:
  AlphaFold DB ─ PubMed/PMC ─ ChEMBL
  Ensembl ─ gnomAD ─ UniProt ─ STRING
  ClinicalTrials.gov ─ Open Targets
  Semantic Scholar ─ Europe PMC

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🤝 Contributing

We welcome contributions! Please see CONTRIBUTING.md for guidelines.

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📄 License

MIT License — see LICENSE for details.

Data from third-party databases is subject to their respective licenses. Please review terms for:

• AlphaFold
• NCBI PubMed
• ChEMBL

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📬 Contact

• Website: biolabmcp.com
• Email: hello@biolabmcp.com
• GitHub Issues: For bug reports and feature requests